Oleoylethanolamide and Human Neural Responses to Food Stimuli in Obesity

Grosshans M, Schwarz E, Bumb JM, Schaefer C, Rohleder C, Vollmert C et al.

(2014) JAMA Psychiatry. Nov;71(11):1254-61.

Link to abstract

Obesity has emerged as a leading health threat but its biological basis remains insufficiently known, hampering the search for novel treatments. Here, we study oleoylethanolamide, a naturally occurring lipid that has been clearly implicated in weight regulation in animals. However, its role for weight regulation and obesity in humans is still unclear.