Lasting effects of repeated ∆9-tetrahydrocannabinol vapour inhalation during adolescence in male and female rats

Nguyen JD, Creehan KM, Kerr TM and Taffe MA

Br J Pharmacol (2020) 177: 188-203

Link to abstract

Adolescents are regularly exposed to ∆⁹ -tetrahydrocannabinol (THC) via smoking and, more recently, vaping cannabis extracts. Growing legalization of cannabis for medical and recreational purposes, combined with decreasing perceptions of harm, makes it increasingly important to determine the consequences of frequent adolescent exposure for motivated behaviour and lasting tolerance in response to THC.