Protective role of neuronal and lymphoid cannabinoid CB2 receptors in neuropathic pain
Cabanero D, Ramirez-Lopez A, Drews E, Schmole A, Otte DM, Wawrzczak-Bargiela A, Huerga Encabo H, Kummer S, Ferrer-Montiel A, Przewlocki…
The Nucleotide-Free State of the Cannabinoid CB2/Gi Complex
Lynch DL, Hurst DP and Reggio PH Cell (2020) 180: 603-604 Link to abstract In this issue of Cell, two…
Endocannabinoid hydrolysis inhibition unmasks that unsaturated fatty acids induce a robust biosynthesis of 2-arachidonoyl-glycerol and its congeners in human myeloid leukocytes
Turcotte C, Archambault AS, Dumais E, Martin C, Blanchet MR, Bissonnette E, Ohashi N, Yamamoto K, Itoh T, Laviolette M,…
Cryo-EM Structure of the Human Cannabinoid Receptor CB2-Gi Signaling Complex
Xing C, Zhuang Y, Xu TH, Feng Z, Zhou XE, Chen M, Wang L, Meng X, Xue Y, Wang J,…
Highly Selective, Amine-Derived Cannabinoid Receptor 2 Probes
Westphal MV, Sarott RC, Zirwes EA, Osterwald A, Guba W, Ullmer C, Grether U and Carreira EM Chemistry (2020) 26:…
Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors
Malamas MS, Farah SI, Lamani M, Pelekoudas DN, Perry NT, Rajarshi G, Miyabe CY, Chandrashekhar H, West J, Pavlopoulos S…
The roles of cannabinoid CB1 and CB2 receptors in cocaine-induced behavioral sensitization and conditioned place preference in mice
Lopes JB, Bastos JR, Costa RB, Aguiar DC and Moreira FA Psychopharmacology (Berl) (2020) 237: 385-394 Link to abstract Cocaine…
CB2 receptor deletion on myeloid cells enhanced mechanical allodynia in a mouse model of neuropathic pain
Nent E, Nozaki C, Schmole AC, Otte D and Zimmer A (2019) Sci Rep 9: 7468 Link to abstract Neuropathic…
The therapeutic role of cannabinoid receptors and its agonists or antagonists in Parkinson’s disease
Han QW, Yuan YH and Chen NH Prog Neuropsychopharmacol Biol Psychiatry (2020) 96: 109745 Link to abstract Parkinson’s disease (PD)…
Cannabidiol attenuates the rewarding effects of cocaine in rats by CB2, 5-HT1A and TRPV1 receptor mechanisms
Galaj E, Bi GH, Yang HJ and Xi ZX Neuropharmacology (2020) 167: 107740 Link to abstract Cocaine abuse continues to…
Therapeutic targeting of HER2-CB2R heteromers in HER2-positive breast cancer
Blasco-Benito S, Moreno E, Seijo-Vila M, Tundidor I, Andradas C, Caffarel MM, Caro-Villalobos M, Uriguen L, Diez-Alarcia R, Moreno-Bueno G,…
Cellular localization and regulation of receptors and enzymes of the endocannabinoid system in intestinal and systemic inflammation
Grill M, Hasenoehrl C, Kienzl M, Kargl J and Schicho R (2018) Histochem Cell Biol. 2018 Sep 8. doi: 10.1007/s00418-018-1719-0….
Cannabinoid Type 2 Receptors Mediate a Cell Type-Specific Plasticity in the Hippocampus
Stempel AV, Stumpf A, Zhang HY, Ozdogan T, Pannasch U, Theis AK, Otte DM, Wojtalla A, Racz I, Ponomarenko A,…
Type 2 cannabinoid receptor contributes to the physiological regulation of spermatogenesis
Di Giacomo D, De Domenico E, Sette C, Geremia R, and Grimaldi P (2015) FASEB J . Apr;30(4):1453-63. Link to…
Palmitoylethanolamide attenuates PTZ-induced seizures through CB1 and CB2 receptors
Aghaei I, Rostampour M, Shabani M, Naderi N, Motamedi F, Babaei P, and Khakpour-Taleghani B 2015) Epilepsy Res, Vol. 117,…
Primary Macrophage Chemotaxis Induced by Cannabinoid Receptor 2 Agonists Occurs Independently of the CB2 Receptor
Taylor, L, Christou, I, Kapellos, TS, Buchan, A, Brodermann, MH, Gianella-Borradori, M, Russell, A, Iqbal, AJ & Greaves, DR. (2015)…