Symmetrically substituted dichlorophenes inhibit N-acyl-phosphatidylethanolamine phospholipase D
Aggarwal G, Zarrow JE, Mashhadi Z, Flynn CR, Vinson P, Weaver CD and Davies SS J Biol Chem (2020) 295:…
Highly Selective, Amine-Derived Cannabinoid Receptor 2 Probes
Westphal MV, Sarott RC, Zirwes EA, Osterwald A, Guba W, Ullmer C, Grether U and Carreira EM Chemistry (2020) 26:…
Endocannabinoid modulating drugs improve anxiety but not the expression of conditioned fear in a rodent model of post-traumatic stress disorder
Vimalanathan A, Gidyk DC, Diwan M, Gouveia FV, Lipsman N, Giacobbe P, Nobrega JN and Hamani C Neuropharmacology (2020) 166:…
Activity-based protein profiling of the human failing ischemic heart reveals alterations in hydrolase activities involving the endocannabinoid system
van Esbroeck ACM, Varga ZV, Di X, van Rooden EJ, Toth VE, Onodi Z, Kusmierczyk M, Leszek P, Ferdinandy P,…
Monoacylglycerol Lipase Inhibition in Human and Rodent Systems Supports Clinical Evaluation of Endocannabinoid Modulators
Clapper JR, Henry CL, Niphakis MJ, Knize AM, Coppola AR, Simon GM, Ngo N, Herbst RA, Herbst DM, Reed AW,…
Endocannabinoid-Specific Impairment in Synaptic Plasticity in Striatum of Huntington’s Disease Mouse Model
Sepers MD, Smith-Dijak A, LeDue J, Kolodziejczyk K, Mackie K and Raymond LA (2018) J Neurosci, 38: 544-554. Link to…
The Endocannabinoid System and Its Therapeutic Exploitation in Multiple Sclerosis: Clues for Other Neuroinflammatory Diseases
Chiurchiu V, van der Stelt M, Centonze D and Maccarrone M. (2018) Prog Neurobiol, 160: 82-100. Link to abstract Multiple…
Maternal high-fat diet induces sex-specific endocannabinoid system changes in newborn rats and programs adiposity, energy expenditure and food preference in adulthood
Dias-Rocha CP, Almeida MM, Santana EM, Costa JCB, Franco JG, Pazos-Moura CC and Trevenzoli IH (2018) J Nutr Biochem, 51:…
Severity of alcohol dependence is associated with the fatty acid amide hydrolase Pro129Thr missense variant
Sloan ME, Gowin JL, Yan J, Schwandt ML, Spagnolo PA, Sun H, Hodgkinson CA, Goldman D and Ramchandani VA (2018)…
Ethanol downregulates N-acyl phosphatidylethanolamine-phospholipase D expression in BV2 microglial cells via epigenetic mechanisms
Correa F, De Laurentiis A, and Franchi AM 2016) Eur J Pharmacol, 782: 224-233 Link to abstract Excessive ethanol drinking…
Effect of endocannabinoid degradation on pain: role of FAAH polymorphisms in experimental and postoperative pain in women treated for breast cancer
Cajanus, K, Holmstrom, EJ, Wessman, M, Anttila, V, Kaunisto, MA, Kalso, E (2016) Pain 157: 361-369 Link to abstract Fatty…
Type 2 cannabinoid receptor contributes to the physiological regulation of spermatogenesis
Di Giacomo D, De Domenico E, Sette C, Geremia R, and Grimaldi P (2015) FASEB J . Apr;30(4):1453-63. Link to…
Deletion of Monoglyceride Lipase in Astrocytes Attenuates Lipopolysaccharide-Induced Neuroinflammation
Grabner GF, Eichmann TO, Wagner B, Gao Y, Farzi A, Taschler U, Radner FP, Schweiger M, Lass A, Holzer P,…
THC and endocannabinoids differentially regulate neuronal activity in the prefrontal cortex and hippocampus in the subchronic PCP model of schizophrenia
Aguilar DD, Giuffrida A, and Lodge DJ (2016) J Psychopharmacol, 30(2):169-81. Link to abstract Cannabis use has been associated with…
Crosstalk between endocannabinoid and immune systems: a potential dysregulation in depression?
Boorman E, Zajkowska Z, Ahmed R, Pariante CM, and Zunszain PA (2016) Psychopharmacology (Berl) . May;233(9):1591-604. Link to abstract The…
beta-Neurexins Control Neural Circuits by Regulating Synaptic Endocannabinoid Signaling
Anderson GR, Aoto J, Tabuchi K, Foldy C, Covy J, Yee AX, Wu D, Lee SJ, Chen L, Malenka RC,…
Endocannabinoids are conserved inhibitors of the Hedgehog pathway
Khaliullina, H., Bilgin, M., Sampaio, J.L., Shevchenko, A., and Eaton, S. (2015) Proc.Natl.Acad.Sci.U.S.A. 112 (11): 3415-3420. Link to abstract Hedgehog…